Mohamed (Moe) Mahjoub, PhD
Mohamed (Moe) Mahjoub, PhD, Assistant Professor of Medicine in the Renal Division and Assistant Professor of Cell Biology and Physiology, along with his co-investigators Steven Brody, MD, PhD (Pulmonary Division) and Susan Dutcher, PhD (Genetics), were awarded a four-year, $2.35 million grant from the National Heart, Lung and Blood Institute (NHLBI) to fund a research project titled “Regulation of Motile Cilia Assembly in Lung Disease.”
Clearance of pathogens and particulates from the airway is an essential function for host defense, and dependent on the combined actions of airway mucus and beating of cilia. Failed ciliary function results in lung infection and the development of chronic lung disease. Dr. Mahjoub and his colleagues aim to identify key mechanisms for the assembly of motile cilia that provide critical points of regulation that can be modified as targets for therapy of lung disease with defective cilia.