Tag: ADTKD-UMOD

Physician-Scientist Ying Maggie Chen Receives VA Merit Award

Congratulations to Associate Professor of Medicine, Ying Maggie Chen, MD, PhD, WashU Nephrology, who received a four-year, $1.15M VA Merit Award from the U.S. Department of Veterans Affairs.  The funding will support her research on therapeutic targeting of mitochondria in uromodulin-associated chronic kidney disease (CKD).  The $1.15M grant award includes the $750,000 grant (direct costs) […]

Ying Maggie Chen Lab and Collaborators Uncover Biotherapeutic Properties of MANF Protein

In their newly-published article in Nature Communications, a multi-center group led by Ying Maggie Chen, MD, PhD, WashU Division of Nephrology, describes previously unknown mechanisms of action of mesencephalic astrocyte-derived neurotrophic factor (MANF) and its therapeutic function, with regards to kidney disease.  MANF is a secreted endoplasmic reticulum (ER) protein that possesses cytoprotective properties. Their […]