Too Many Centrosomes Spoil the Kidney

Assistant Professor of Medicine Moe Mahjoub, PhD, discovered that, yes, there can be “too much of a good thing.” Dr. Mahjoub’s new study, published in the July issue of the Journal of Cell Biology, found that formation of excess centrosomes is detrimental to renal development and is sufficient to trigger cyst formation independently of cystic […]

Study Defines a Novel Molecular Defect Underlying Renal Cystogenesis

Joubert syndrome and Jeune Asphyxiating Thoracic Dystrophy (JATD) are human disorders characterized by multi-organ pathologies including neurocognitive defects, musculoskeletal malformations, respiratory distress and retinal degeneration, among others.