Congratulations to Ying Maggie Chen, MD, PhD, Associate Professor of Medicine in the Division of Nephrology, and co-inventors, Sun-Ji Park, PhD, Yeawon Kim, and Fumihiko Urano on their patent “Compositions and methods for treating and preventing endoplasmic reticulum (ER) stress-mediated kidney diseases” that was issued on September 28, 2021. The ER plays important roles […]
Congratulations to Ying “Maggie” Chen, MD, PhD, Assistant Professor of Medicine, Nephrology, who was awarded a $1.8 million grant (total cost) from the U.S. Department of Defense for her study “Development of Novel Podocyte Endoplasmic Reticulum (ER) Calcium Stabilizers to Treat Focal Segmental Glomerulosclerosis (FSGS).” FSGS is the most common primary glomerulopathy leading to renal […]
Ying Maggie Chen, MD, PhD, Assistant Professor of Medicine, Nephrology, is the recipient of a 2-year, $300,000 Mallinckrodt Challenge Grant for her study “Targeting Podocyte Dysfunctional Ryanodine Receptor to Treat Nephrotic Syndrome.” “The overall goals of this proposal are to determine the molecular mechanisms underlying increased podocyte endoplasmic reticulum (ER) calcium efflux under ER stress […]
A new study led by Ying Maggie Chen, MD, PhD, Division of Nephrology, found a new class of drugs that shows great promise in the treatment of nephrotic syndrome (NS) resulting from podocyte endoplasmic reticulum (ER) dysfunction. NS is a leading cause of chronic kidney disease affecting over 500 million people worldwide. Damage to podocytes, […]