The Division of Nephrology is proud to announce that the American Society for Clinical Investigation (ASCI) has elected Ying Maggie Chen, MD, PhD, Associate Professor of Medicine, into its 2022 class of members. Founded in 1908, ASCI is one of the oldest and most esteemed nonprofit honor societies of physician-scientists. Dr. Chen is a nephrotic […]
Tag: er stress biomarkers
New Nanotechnique Monitors ER Stress Biomarker for ADTKD
WashU Nephrology researchers are part of a group of scientists who have used a new technique that significantly boosts detection and quantification of low-abundance molecular biomarkers in urine to study an underdiagnosed cause of kidney disease. Yeawon Kim, a member of the Y. Maggie Chen Lab, is first author of the study titled “Ultrabright Plasmonic-Fluor […]
Dr. Ying Maggie Chen to Present at the 2021 FASEB ER Virtual Conference
Ying Maggie Chen, MD, PhD, Associate Professor of Medicine in the Division of Nephrology at Washington University in St. Louis, will present at the 2021 FASEB Endoplasmic Reticulum (ER) Conference: Structure, Function, and Disease virtual conference to be held June 22-24, 2021. Dr Chen will speak on Endoplasmic Reticulum Dyshomeostasis and Kidney Disease. This FASEB […]
Promising Therapies for the Treatment of Podocyte Endoplasmic Reticulum Stress-induced NS/FSGS
A new study led by Ying Maggie Chen, MD, PhD, Division of Nephrology, found a new class of drugs that shows great promise in the treatment of nephrotic syndrome (NS) resulting from podocyte endoplasmic reticulum (ER) dysfunction. NS is a leading cause of chronic kidney disease affecting over 500 million people worldwide. Damage to podocytes, […]
Broad Clinical Applications for CRELD2 as an ER Stress Biomarker
Thanks to a new study headed by Ying Maggie Chen, MD, PhD, it may soon be possible to diagnose certain human kidney diseases in their earliest stages of development using a noninvasive biomarker of endoplasmic reticulum (ER) stress. The study, Elevated Urinary CRELD2 is Associated with Endoplasmic Reticulum Stress-mediated Kidney Disease, was published online in […]