Tag: genomics

Functional Genomic Study Sheds Light on New Treatment Opportunities for EGFR-driven CKD

A group of scientists led by Associate Professor of Medicine Andreas Herrlich, Division of Nephrology, has used a functional genomics approach to identify key signaling pathways as novel regulators of transforming growth factor-alpha (TGFα) shedding in cancer cells. The article is published in the January 2018 issue of Molecular Cancer Research. (MCR) Ectodomain shedding (or, […]

Expanded Genomic Profiling for Renal Diseases at WashU

In the complex world of renal pathology, a kidney biopsy is often not enough to make a definitive diagnosis in certain patients. This is when diagnostic genetic testing can help. Genetic testing using next-generation sequencing (NGS; also known as high-throughput sequencing) is fast becoming a valuable tool for clinicians to help manage complicated cases and […]