In their newly-published article in Nature Communications, a multi-center group led by Ying Maggie Chen, MD, PhD, WashU Division of Nephrology, describes previously unknown mechanisms of action of mesencephalic astrocyte-derived neurotrophic factor (MANF) and its therapeutic function, with regards to kidney disease. MANF is a secreted endoplasmic reticulum (ER) protein that possesses cytoprotective properties. Their […]