Tag: umod

New Clinic Will Help Patients with Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD)

A new clinic at WashU Nephrology will focus on helping patients with a genetic form of renal fibrosis – autosomal dominant tubulointerstitial kidney disease (ADTKD) – which ultimately leads to chronic kidney disease (CKD). After exclusion of polycystic kidney disease and Alport syndrome, ADTKD represents as many as 25% of patients with inherited kidney disease. […]

Broad Clinical Applications for CRELD2 as an ER Stress Biomarker

Thanks to a new study headed by Ying Maggie Chen, MD, PhD, it may soon be possible to diagnose certain human kidney diseases in their earliest stages of development using a noninvasive biomarker of endoplasmic reticulum (ER) stress. The study, Elevated Urinary CRELD2 is Associated with Endoplasmic Reticulum Stress-mediated Kidney Disease, was published online in […]