Location

Patients seen at

Patients seen at

Mailing Address

Additional Titles

• Director,  Kidney Transplant Clinic at Veterans Affairs St. Louis Health Care System

Education

• Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.): Government Medical College, Nagpur, India (2002)
• Externship Internal Medicine: St. John’s Regional Medical Center and Freeman Health System, Joplin, MO (2004)
• Residency in Internal Medicine: Orlando Regional Medical Center, Orlando, FL (2010)
• Fellowship in Transplant Nephrology: Washington University School of Medicine in St. Louis, St. Louis, MO (2012)

Board Certifications

• ABIM Board Certified in Internal Medicine, 2005
• ABIM Board Certified in Nephrology, 2008

Recognition

2006
Best Primary Care Physician Award; PGY1, Internal Medicine

2007
ACP Clinical Vignette Finalist (Florida Chapter)

2008
Chief Resident Award; PGY3, Internal Medicine

2012
Travel award to attend the “AST Fellows Symposium” in Grapevine, Texas

2013
Travel award to attend “Origins of Renal Physiology” workshop for Fellows at the Mount Desert Island Biological Laboratory (MDIBL), Bar Harbor, Maine

Clinical Interests

Kidney transplantation, recurrent glomerulonephritis, chronic kidney disease and fluid and electrolyte disorders.

Research Interests

Investigating the role of complement receptors and regulators in the pathogenesis of immune and inflammatory processes in the kidney.

In particular, she is interested in defining the functional consequences of genetic mutations identified in complement-mediated kidney diseases such as atypical hemolytic uremic syndrome and C3 glomerulopathy.

Publications

Java A, Gaut JP, Brennan DC, De Novo Membranoproliferative Glomerulonephritis III in a Renal Transplant Patient: Case Report and Review of the Literature”. Transpl Int. 2012 May; 25(5):e58-61. doi: 10.1111/j.1432-2277.2012.01452.x.

Java A, Edwards A, Rossi A, Pandey R, Gaut J, Delos Santos R, Miller B, Klein C, Brennan D, Cytomegalovirus-induced thrombotic microangiopathy after renal transplant successfully treated with eculizumab: Case report and review of the literature. Transpl Int. 2015 Sep; 28(9):1121-5. doi: 10.1111/tri.12582.

Java A, Liszewski MK, Hourcade DE , Zhang F, Atkinson J, Role of Complement receptor 1 (CR1) on epithelial cells: A model for understanding complement-mediated damage in the kidney. Mol Immunol. 2015 Aug 7. pii: 0161-5890(15)30024-9. doi: 10.1016/j.molimm.2015.07.016.

Chauvet S, Roumenina L, Marinozzi M, Rybkine T, Schramm E, Java A, Atkinson J, Aldigier, J, Bridoux F, Touchard G, Bacchi V. A familial C3GN secondary to defective C3 regulation by CR1 and FH. JASN. In press.

Java A, Cheng X, and Brennan DC. Polyomavirus Infections of Humans. In: eLS. John Wiley & Sons Ltd, Chichester. April 2012

Schramm E, Java A, Liszewski K, Atkinson J. Complement deficiencies associated with atypical hemolytic uremic syndrome. Encyclopedia of Medical immunology. In press.

Java A, Brennan DC. Recurrence of C3 glomerulopathies after transplantation. UpToDate, www.uptodate.com (version 2.0), Jan 2015.

Java A, Brennan DC. Recurrence of idiopathic immune complex-mediated membranoproliferative glomerulonephritis (MPGN) after transplantation. UpToDate, www.uptodate.com (version 15.0), Feb 2015.

Java A, Atkinson J, Salmon JE. Defective Complement Inhibitory Function Predisposes to Renal Disease. Annual Review of Medicine. 2013 January; 64:307-324.