Refining the Recipe to Turn Stem Cells into Kidney Cells

The science of coaxing stem cells into kidney cells just became a little more refined. Researchers in the Humphreys Laboratory in the Division of Nephrology at Washington University show that protocols used to grow kidney organoids from human stem cells can be modified to produce more kidney-specific cells and less “off-target” contaminating cells. Organoids are […]

WU Nephrology Publication Highlighted at New ASN Kidney Week Session

The American Society of Nephrology debuted a new session at Kidney Week 2018, held last month in San Diego, CA, that featured 29 cutting edge, high-impact publications in the Clinical Journal of the American Society of Nephrology (CJASN) and the Journal of the American Society of Nephrology (JASN) over the past year. The session, called […]

scRNA-seq is a Game Changer in Kidney Biopsy Cell Characterization

Researchers in the Division of Nephrology are using a state-of-the-art technique called single-cell RNA-sequencing (scRNA-seq) to take kidney biopsy interpretation to a whole new level. Their study, recently published in JASN, presents the first scRNA-seq analysis of a human kidney allograft biopsy. Instructor of Medicine Haojia Wu, PhD, and Assistant Professor of Medicine Andrew Malone, […]

WU Nephrology Integral Part in CZI Push to Accelerate Scientific Discovery

The Chan-Zuckerberg Initiative (CZI), founded by Facebook co-founder and CEO Mark Zuckerberg and his wife, pediatrician Priscilla Chan, has an ambitious goal: to help scientists cure, manage, or prevent all disease by the end of the century. As part of that goal, in 2017, CZI funded 38 pilot projects to contribute to the Human Cell […]