Refining the Recipe to Turn Stem Cells into Kidney Cells

The science of coaxing stem cells into kidney cells just became a little more refined. Researchers in the Humphreys Laboratory in the Division of Nephrology at Washington University show that protocols used to grow kidney organoids from human stem cells can be modified to produce more kidney-specific cells and less “off-target” contaminating cells. Organoids are […]

scRNA-seq is a Game Changer in Kidney Biopsy Cell Characterization

Researchers in the Division of Nephrology are using a state-of-the-art technique called single-cell RNA-sequencing (scRNA-seq) to take kidney biopsy interpretation to a whole new level. Their study, recently published in JASN, presents the first scRNA-seq analysis of a human kidney allograft biopsy. Instructor of Medicine Haojia Wu, PhD, and Assistant Professor of Medicine Andrew Malone, […]