John T. Milliken Department of Medicine
Thanks to a new study headed by Ying Maggie Chen, MD, PhD, it may soon be possible to diagnose certain human kidney diseases in their earliest stages of development using a noninvasive biomarker of endoplasmic reticulum (ER) stress. The study, Elevated Urinary CRELD2 is Associated with Endoplasmic Reticulum Stress-mediated Kidney Disease, was published online in […]
A review article by the group of Ying Maggie Chen, MD, PhD, Assistant professor of Medicine, Nephrology, was published as part of the Featured New Investigator series in the journal Translational Research. The article, Mesencephalic astrocyte-derived neurotrophic factor (MANF), a new player in endoplasmic reticulum diseases: structure, biology, and therapeutic roles, is based on first […]
ASN Kidney Week 2017 will be held at the Ernest N. Morial Convention Center in New Orleans, LA, Tuesday October 31 through Sunday November 5. Below is a list of those in the Division of Nephrology and Pediatric Nephrology who have abstracts, oral Presentations or will moderate sessions. Wednesday, November 1 Anitha Vijayan, MD, Professor […]
Congratulations to Assistant Professor of Medicine Ying (Maggie) Chen, MD, PhD, who has been awarded a five-year $1.52M total costs, R01 grant from the NIH to fund a research project titled Podocyte Endoplasmic Reticulum Stress and Nephrotic Syndrome. Nephrotic syndrome (NS), characterized by heavy proteinuria and increased risk of loss of kidney function, causes serious […]
A case report by a team of Washington University nephrologists and pathologists from Arkana Laboratories may prove valuable in directing future treatment of Castleman’s Disease (CD) with renal involvement. The report, published in the journal BMC Nephrology, describes a patient presenting with a very rare, aggressive form of multicentric CD with renal thrombotic microangiopathy (TMA). […]
Hani Suleiman, MD, PhD, has been awarded a Nephrotic Syndrome Study Network (NEPTUNE) Career Development Fellowship for his grant “Sarcomere-Like Structures” as an Indicator for Podocyte Injury in Nephrotic Syndrome. The NEPTUNE program uses a multidisciplinary approach that brings together academic medical centers, patient advocacy groups (NephCure Foundation and the Halpin Foundation), and clinical research […]
Angiopoietin-1 (Ang-1), a vascular growth factor secreted by kidney proximal tubular cells, pericytes and podocytes, is essential for regulating blood vessel development and repair after injury. Ang-1 is also a promising therapeutic agent to target renal fibrosis, according to a study by WU researchers recently published in PLoSOne, As a result of injury to the […]