Tag: masato hoshi

Too Many Centrosomes Spoil the Kidney

Assistant Professor of Medicine Moe Mahjoub, PhD, discovered that, yes, there can be “too much of a good thing.” Dr. Mahjoub’s new study, published in the July issue of the Journal of Cell Biology, found that formation of excess centrosomes is detrimental to renal development and is sufficient to trigger cyst formation independently of cystic […]

The Kiss of Life and Death in the Making of the Kidney and Urinary Tract

The spectrum of congenital anomalies of the kidneys and urinary tract, known as CAKUT, represents more than 20% of all birth defects and constitutes the largest cause of kidney failure in children. A new study by Dr. Masato Hoshi, a Senior Scientist in the laboratory of Associate Professor of Medicine, Sanjay Jain, Division of Nephrology, […]