Gene Therapy Study Using AAV-based Vectors Lays Foundation for Kidney Fibrosis Treatment

Renal fibrosis, a hallmark of chronic kidney disease (CKD), is characterized by the accumulation of excess extracellular matrix proteins secreted by myofibroblasts. Unfortunately, there are no anti-fibrotic drugs approved for treatment of CKD. A new study headed by researchers in the Humphreys Laboratory in the Division of Nephrology at Washington University, however, is laying the […]