Dr. Benjamin Humphreys Profiled in Washington People

Dr. Benjamin Humphreys, MD, PhD, Joseph Friedman Professor of Renal Diseases in Medicine and director of the Division of Nephrology, is the subject of Washington University School of Medicine’s Washington People, a series that profiles individuals throughout the medical campus and community. In the profile, Humphreys talks about the exciting future for the field of […]

scRNA-seq is a Game Changer in Kidney Biopsy Cell Characterization

Researchers in the Division of Nephrology are using a state-of-the-art technique called single-cell RNA-sequencing (scRNA-seq) to take kidney biopsy interpretation to a whole new level. Their study, recently published in JASN, presents the first scRNA-seq analysis of a human kidney allograft biopsy. Instructor of Medicine Haojia Wu, PhD, and Assistant Professor of Medicine Andrew Malone, […]

Gene Therapy Study Using AAV-based Vectors Lays Foundation for Kidney Fibrosis Treatment

Renal fibrosis, a hallmark of chronic kidney disease (CKD), is characterized by the accumulation of excess extracellular matrix proteins secreted by myofibroblasts. Unfortunately, there are no anti-fibrotic drugs approved for treatment of CKD. A new study headed by researchers in the Humphreys Laboratory in the Division of Nephrology at Washington University, however, is laying the […]

WU Nephrology Integral Part in CZI Push to Accelerate Scientific Discovery

The Chan-Zuckerberg Initiative (CZI), founded by Facebook co-founder and CEO Mark Zuckerberg and his wife, pediatrician Priscilla Chan, has an ambitious goal: to help scientists cure, manage, or prevent all disease by the end of the century. As part of that goal, in 2017, CZI funded 38 pilot projects to contribute to the Human Cell […]