Division’s scRNA-seq Research Makes NephJC and JASN Top Stories Lists for 2018

Congratulations to investigators in our division whose research using single cell RNA sequencing (scRNA-seq) was highlighted as one of the top nephrology stories of 2018 at NephJC, a nephrology journal club that uses Twitter to discuss the latest news in nephrology, and the scientific journal JASN. The topic of scRNA-seq came in at number nine […]

Refining the Recipe to Turn Stem Cells into Kidney Cells

The science of coaxing stem cells into kidney cells just became a little more refined. Researchers in the Humphreys Laboratory in the Division of Nephrology at Washington University show that protocols used to grow kidney organoids from human stem cells can be modified to produce more kidney-specific cells and less “off-target” contaminating cells. Organoids are […]

WU Nephrology Publication Highlighted at New ASN Kidney Week Session

The American Society of Nephrology debuted a new session at Kidney Week 2018, held last month in San Diego, CA, that featured 29 cutting edge, high-impact publications in the Clinical Journal of the American Society of Nephrology (CJASN) and the Journal of the American Society of Nephrology (JASN) over the past year. The session, called […]

scRNA-seq is a Game Changer in Kidney Biopsy Cell Characterization

Researchers in the Division of Nephrology are using a state-of-the-art technique called single-cell RNA-sequencing (scRNA-seq) to take kidney biopsy interpretation to a whole new level. Their study, recently published in JASN, presents the first scRNA-seq analysis of a human kidney allograft biopsy. Instructor of Medicine Haojia Wu, PhD, and Assistant Professor of Medicine Andrew Malone, […]

Study Details Origin of Myofibroblasts Responsible for Kidney Fibrosis

The results of an international collaboration of researchers including Dr. Benjamin Humphreys, Division of Nephrology at Washington University, and Dr. Rafael Kramann, Division of Nephrology and Clinical Immunology at RWTH Aachen University in Germany, published in the May issue of JCI insight, settles the years-old controversy of the origin of scar-forming macrophages in the kidney. […]

WU Nephrology Integral Part in CZI Push to Accelerate Scientific Discovery

The Chan-Zuckerberg Initiative (CZI), founded by Facebook co-founder and CEO Mark Zuckerberg and his wife, pediatrician Priscilla Chan, has an ambitious goal: to help scientists cure, manage, or prevent all disease by the end of the century. As part of that goal, in 2017, CZI funded 38 pilot projects to contribute to the Human Cell […]