Tag: single-cell rna

scRNA-seq is a Game Changer in Kidney Biopsy Cell Characterization

Researchers in the Division of Nephrology are using a state-of-the-art technique called single-cell RNA-sequencing (scRNA-seq) to take kidney biopsy interpretation to a whole new level. Their study, recently published in JASN, presents the first scRNA-seq analysis of a human kidney allograft biopsy. Instructor of Medicine Haojia Wu, PhD, and Assistant Professor of Medicine Andrew Malone, […]

Study Details Origin of Myofibroblasts Responsible for Kidney Fibrosis

The results of an international collaboration of researchers including Dr. Benjamin Humphreys, Division of Nephrology at Washington University, and Dr. Rafael Kramann, Division of Nephrology and Clinical Immunology at RWTH Aachen University in Germany, published in the May issue of JCI insight, settles the years-old controversy of the origin of scar-forming macrophages in the kidney. […]